256 Steven johnsons syndrome/toxic epidermal necrolysis management in the burn intensive care unit

نویسندگان

چکیده

Background: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis comprise a spectrum of severe hypersensitivity skin reactions. is the least on mucosal erosions, with being most severe. Syndrome/Toxic disease keratinocytes therefore any squamous cell epithelium at risk. This includes cornea, conjunctiva, oral mucosa, esophagus, urethra, anal canal. reaction typically drug-induced has very poor prognosis. Methods: Study personnel identified potential subject records for study using electronic medical University Medical Hospital. We obtained spreadsheet identifiable patient information from office by searching ICD-10 codes pertaining to causes necessitating treatment SJS including L53.1 (Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome), L00-99 (Diseases subcutaneous tissue), L49-54 (urticaria erythema), L51 (erythema multiforme). Results: present an analysis mortality patients who managed solely in burn intensive care unit our facility. The mainstay included supportive emphasis fluid electrolyte replacement. Transfer not current standard care, however could decrease morbidity patients. As seen centers only had rate 17% over 5 years. Management comprehensive interdisciplinary wound team rather than dermatological intervention may improve outcomes. Conclusion: however, Burn Intensive Care Unit decreases mortality.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Clinical Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Efficacy of Treatment in Burn Intensive Care Unit

133 Correspondence to: Yong Suk Cho, Department of General Surgery, Hangang Sacred Heart Hospital, Hallym University Medical Center, 94-200, Yeongdeungpo-dong 7-ga, Yeongdeungpo-gu, Seoul 150719, Korea. Tel: 02-2639-5442, Fax: 02-2678-4386, E-mail: [email protected] Received October 5, 2009, Accepted December 18, 2009 A Clinical Study of Stevens-Johnson Syndrome and Toxic Epidermal Necroly...

متن کامل

Intensive Care in a Patient with Toxic Epidermal Necrolysis

Toxic epidermal necrolysis (TEN) is a serious adverse drug reaction with high lethality, which usually requires intensive-medical care. A 44-year-old man developed generalized exanthema with increasing exfoliation and mucosal involvement after taking allopurinol, ibuprofen, and etoricoxib. The clinical diagnosis of TEN was histologically confirmed. Prednisolone therapy with 3 mg/kg body weight ...

متن کامل

Toxic epidermal necrolysis and Steven-Johnson syndrome in oncologic patients.

BACKGROUND AND OBJECTIVES We reviewed our case-load of patients with Toxic Epidermal Necrolysis (TEN) and analysed this oncologic disease in order to define the prevalence of this comorbidity and find eventual clinical and prognostic differences, specific of this subgroup of patients. MATERIALS AND METHODS We reviewed charts from January 1995 to December 2005. Only those patients with a TEN d...

متن کامل

Dermatology in the intensive care unit

Background: Considering the prevalence of skin lesions and drug eruptions in intensive care units and the absence of research about it, we decided to study skin lesions of patients admitted in intensive care unit. Patients and Methods: In this descriptive study all patients admitted in intensive care units of Al-Zahra Hospital in Isfahan in 1376-78 were observed and examined by a resident in De...

متن کامل

Toxic Epidermal Necrolysis From a Cigarette Burn

Toxic epidermal necrolysis is a rare disease that is most often drug-induced but can be of idiopathic origin. We present a case that originated at the site of a cigarette burn to the forearm and review the key elements of physical exam findings and management of this life-threatening dermatological condition, which needs to be promptly recognized to decrease patient mortality.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2022

ISSN: ['1523-1747', '0022-202X']

DOI: https://doi.org/10.1016/j.jid.2022.05.263